Answer:
Huntington`s Disease
Findings:
FH to IC ratio is reduced -1.2 Significant Bicaudate nucleus atrophy with Box like Frontal Horns. Bilateral putaminal volume loss.
Discussion:
Patient presented with Involuntary movements . The finding of isolated caudate nucleus atrophy in an adult patient with movement disorder and dementia /psychosis is typical of Huntingdon`s Disease. The other differential diagnoses are : Pantothenate Kinase Associated Neurodegeneration –Typical Eye of Tiger sign (T2 hyperintense foci in Globus Pallidus with surrounding T2 hypointensity) Wilson`s Disease – Clinical KF ring associated with radiological abnormalities in basal ganglia , thalamus and midbrain.
Contributed By:
Dr. Babu Peter MD, DNB
Associate Professor, Barnard Institute of Radiology, Chennai
Senior Consultant Radiologist, Aarthi Scans, Chennai
Huntington`s Disease
Findings:
FH to IC ratio is reduced -1.2 Significant Bicaudate nucleus atrophy with Box like Frontal Horns. Bilateral putaminal volume loss.
Discussion:
Patient presented with Involuntary movements . The finding of isolated caudate nucleus atrophy in an adult patient with movement disorder and dementia /psychosis is typical of Huntingdon`s Disease. The other differential diagnoses are : Pantothenate Kinase Associated Neurodegeneration –Typical Eye of Tiger sign (T2 hyperintense foci in Globus Pallidus with surrounding T2 hypointensity) Wilson`s Disease – Clinical KF ring associated with radiological abnormalities in basal ganglia , thalamus and midbrain.
Contributed By:
Dr. Babu Peter MD, DNB
Associate Professor, Barnard Institute of Radiology, Chennai
Senior Consultant Radiologist, Aarthi Scans, Chennai