Answer for BIR CoW 31 May 2026
PARTIAL DYSGENESIS OF CORPUS CALLOSUM
Findings
Bilateral widely placed lateral ventricles noted with parallely arranged thick longitudinal band of white matter bundles seen along medial aspect of bilateral lateral ventricles. Non visualization of rostrum, body and splenium of corpus callosum, fornix, septum pellucidum noted. Posterior aspect of cingulate gyrus not visualized. Disproportionate dilatation of occipital horn of bilateral lateral ventricle noted Impression : Partial dysgenesis of corpus callosum with colpocephaly.
Discussion
Dysgenesis of the corpus callosum may be complete (agenesis) or partial (dysgenesis) and represents an in utero developmental anomaly. It can be divided into: primary agenesis: corpus callosum never forms secondary dysgenesis: corpus callosum forms normally and is subsequently destroyed Associations;
ANEUPLOIDY SYNDROME trisomy 18 trisomy 13 trisomy 8 9
NON-ANEUPLOIDY SYNDROME Aicardi syndrome Apert syndrome Bickers Adams Edwards syndrome Coffin-Siris syndrome fetal alcohol syndrome Fryns syndrome Gorlin syndrome hydrolethalus syndrome Lowe syndrome
IMAGING FINDINGS ;
MRI is the modality of choice in evaluating both the corpus callosum and the frequently associated anomalies. Features include: ventricles run parallel rather than the normal "bow-tie" configuration giving a racing car appearance on axial imaging colpocephaly (dilatation of the trigones and occipital horns) gives a characteristic "Texas longhorn"/moose head/viking helmet appearance on coronal imaging dilated high-riding 3rd ventricle appears to communicate with the interhemispheric cistern or project superiorly as a dorsal cyst cortex bundles of Probst radial gyri (absent cingulate gyrus) everted cingulate gyrus limbic system hypoplastic fornices hypoplastic hippocampi
Findings
Bilateral widely placed lateral ventricles noted with parallely arranged thick longitudinal band of white matter bundles seen along medial aspect of bilateral lateral ventricles. Non visualization of rostrum, body and splenium of corpus callosum, fornix, septum pellucidum noted. Posterior aspect of cingulate gyrus not visualized. Disproportionate dilatation of occipital horn of bilateral lateral ventricle noted Impression : Partial dysgenesis of corpus callosum with colpocephaly.
Discussion
Dysgenesis of the corpus callosum may be complete (agenesis) or partial (dysgenesis) and represents an in utero developmental anomaly. It can be divided into: primary agenesis: corpus callosum never forms secondary dysgenesis: corpus callosum forms normally and is subsequently destroyed Associations;
ANEUPLOIDY SYNDROME trisomy 18 trisomy 13 trisomy 8 9
NON-ANEUPLOIDY SYNDROME Aicardi syndrome Apert syndrome Bickers Adams Edwards syndrome Coffin-Siris syndrome fetal alcohol syndrome Fryns syndrome Gorlin syndrome hydrolethalus syndrome Lowe syndrome
IMAGING FINDINGS ;
MRI is the modality of choice in evaluating both the corpus callosum and the frequently associated anomalies. Features include: ventricles run parallel rather than the normal "bow-tie" configuration giving a racing car appearance on axial imaging colpocephaly (dilatation of the trigones and occipital horns) gives a characteristic "Texas longhorn"/moose head/viking helmet appearance on coronal imaging dilated high-riding 3rd ventricle appears to communicate with the interhemispheric cistern or project superiorly as a dorsal cyst cortex bundles of Probst radial gyri (absent cingulate gyrus) everted cingulate gyrus limbic system hypoplastic fornices hypoplastic hippocampi
Note:
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!