Answer for BIR CoW 12 Jul 2026
PARTIAL SACRAL AGENESIS WITH ANTERIOR SACRAL MENINGOCOELE
Findings
Well defined rounded central anterior defect of S3 vertebra noted with T2 hyperintense cystic lesion showing facilitated diffusion extending from its central canal, occupying the presacral region causing anterior displacement of rectum measuring ~ 7 x 7 x 5.5 cm . No evidence of any neural elements noted within the cystic lesion. Partial agenesis of S3 vertebra with complete agenesis of S4, S5 and coccygeal vertebra along with its posterior element. IMPRESSION: Features of Anterior sacral Meningocele with partial sacral agenesis.
Discussion
Anterior sacral meningocele is a unilocular or multilocular extension of the dura mater and arachnoid out of the sacral spinal canal into the retroperitoneal and infraperitoneal space, either anteriorly through the body of the sacrum or anterolaterally through an enlarged intervertebral foramen or coalesced foramina. The embryogenesis of ASM is not determined. A relatively simple form arises in patients with neurofibromatosis type I and patients with Marfan syndrome. A more complex form is associated with the Currarino triad of anorectal malformations, sacral defects and presacral masses. A familial form with concurrent ASM, tethered cord, lipomas, teratomas and dermoids may be inherited in families as an autosomal dominant trait with incomplete penetrance. They are less common than posterior lumbosacral meningoceles, which are easily diagnosed at birth. ASM accounts for 3-5% of retrorectal masses (1). In adults, females appear to be affected more commonly (approximately 10:6). However, the lesion is equally frequent in boys and girls below age 15, suggesting that increased detection of ASMs during pregnancy accounts for the female predominance in adult patients. The meningocele can enlarge with time, probably as the result of hydrostatic pressure created by the CSF within it. When it enlarges, it does so slowly, and the meningocele may not give rise to symptoms until adult life. Clinical symptoms in ASM are produced as a result of pressure on the pelvic viscera, causing constipation, urinary frequency and incontinence, dysmenorrhea, dyspareunia, or pain in the lower back or pelvis. Furthermore, pressure may be exerted on nerve roots, resulting in sciatica, diminished rectal and detrusor tone, or numbness and paresthesia in the lower sacral dermatomes. Finally, fluid shifts between the sac and the spinal subarachnoid space can cause intermittent high-pressure headache (when supine), nausea, vomiting (especially during defecation), or low-pressure headache (while in the erect position). In imaging studies, plain radiographs may demonstrate sacral bony anomalies: the coccyx and one side of the lower sacrum at one or more levels are absent giving a suggestive “scimitar” aspect of sacrum. In approximately 20% of cases, the sacral defect is in the midline. US of the pelvis demonstrates the fluid-filled lesion, which can be misinterpreted as an ovarian cyst in females and as a bladder in males. Associated uterine malformations may be present. CT and MRI clearly depict the anterior sacral bony defect and the fluid-containing presacral lesion, if CT is used, contrast should be injected intrathecally to optimally show the continuity of the meningocele with the subarachnoid space. On MR studies, the continuity is best demonstrated dynamically in the sagittal plane. Whatever imaging technique is used, the most important features to demonstrate are (a) tethering of cord and the associated tethering lipoma or dermoid, if present, and (b) whether nerve roots traverse the sacral defect
References:
[1] URL:https://www.eurorad.org/case/708 DOI:10.1594/EURORAD/CASE.708
[2] Schneider MB, Dittmar S, Boxer RA. Anterior sacral meningocele presenting as a patient with marfan syndrome. J Adolesc Health 1993;14:325-328. (PMID: 8347646)
[3] Thomas M, Halaby FA, Hirshauer JS. Hereditery occurence of anterior sacral meningocele: report of ten cases. Spine 1987;12:351-354. (PMID: 3616749)
Findings
Well defined rounded central anterior defect of S3 vertebra noted with T2 hyperintense cystic lesion showing facilitated diffusion extending from its central canal, occupying the presacral region causing anterior displacement of rectum measuring ~ 7 x 7 x 5.5 cm . No evidence of any neural elements noted within the cystic lesion. Partial agenesis of S3 vertebra with complete agenesis of S4, S5 and coccygeal vertebra along with its posterior element. IMPRESSION: Features of Anterior sacral Meningocele with partial sacral agenesis.
Discussion
Anterior sacral meningocele is a unilocular or multilocular extension of the dura mater and arachnoid out of the sacral spinal canal into the retroperitoneal and infraperitoneal space, either anteriorly through the body of the sacrum or anterolaterally through an enlarged intervertebral foramen or coalesced foramina. The embryogenesis of ASM is not determined. A relatively simple form arises in patients with neurofibromatosis type I and patients with Marfan syndrome. A more complex form is associated with the Currarino triad of anorectal malformations, sacral defects and presacral masses. A familial form with concurrent ASM, tethered cord, lipomas, teratomas and dermoids may be inherited in families as an autosomal dominant trait with incomplete penetrance. They are less common than posterior lumbosacral meningoceles, which are easily diagnosed at birth. ASM accounts for 3-5% of retrorectal masses (1). In adults, females appear to be affected more commonly (approximately 10:6). However, the lesion is equally frequent in boys and girls below age 15, suggesting that increased detection of ASMs during pregnancy accounts for the female predominance in adult patients. The meningocele can enlarge with time, probably as the result of hydrostatic pressure created by the CSF within it. When it enlarges, it does so slowly, and the meningocele may not give rise to symptoms until adult life. Clinical symptoms in ASM are produced as a result of pressure on the pelvic viscera, causing constipation, urinary frequency and incontinence, dysmenorrhea, dyspareunia, or pain in the lower back or pelvis. Furthermore, pressure may be exerted on nerve roots, resulting in sciatica, diminished rectal and detrusor tone, or numbness and paresthesia in the lower sacral dermatomes. Finally, fluid shifts between the sac and the spinal subarachnoid space can cause intermittent high-pressure headache (when supine), nausea, vomiting (especially during defecation), or low-pressure headache (while in the erect position). In imaging studies, plain radiographs may demonstrate sacral bony anomalies: the coccyx and one side of the lower sacrum at one or more levels are absent giving a suggestive “scimitar” aspect of sacrum. In approximately 20% of cases, the sacral defect is in the midline. US of the pelvis demonstrates the fluid-filled lesion, which can be misinterpreted as an ovarian cyst in females and as a bladder in males. Associated uterine malformations may be present. CT and MRI clearly depict the anterior sacral bony defect and the fluid-containing presacral lesion, if CT is used, contrast should be injected intrathecally to optimally show the continuity of the meningocele with the subarachnoid space. On MR studies, the continuity is best demonstrated dynamically in the sagittal plane. Whatever imaging technique is used, the most important features to demonstrate are (a) tethering of cord and the associated tethering lipoma or dermoid, if present, and (b) whether nerve roots traverse the sacral defect
References:
[1] URL:https://www.eurorad.org/case/708 DOI:10.1594/EURORAD/CASE.708
[2] Schneider MB, Dittmar S, Boxer RA. Anterior sacral meningocele presenting as a patient with marfan syndrome. J Adolesc Health 1993;14:325-328. (PMID: 8347646)
[3] Thomas M, Halaby FA, Hirshauer JS. Hereditery occurence of anterior sacral meningocele: report of ten cases. Spine 1987;12:351-354. (PMID: 3616749)
Note:
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!