Answer for BIR CoW 03 May 2026
SEPTO-OPTIC DYSPLASIA
Findings
Evidence of absence of septum pellucidum with fusion of frontal horns and body of bilateral lateral ventricles in midline. Evidence of cerebrospinal fluid filled linear cleft extending from ependymal surface of body of right lateral ventricle opening into pial surface of parietal region, lined by thickened grey matter with irregular margin of lateral ventricle. Thinning of bilateral optic nerves and optic chiasma noted. Right Perisylvian polypachygyriform complex noted. Interhemispheric fissure noted. Features suggstive of septo optic dysplasia with right parietal open lip schizencephaly and right perisylvian polypachygyria.
Discussion
Septo-optic dysplasia , also known as de Morsier syndrome, is a condition characterised by optic nerve/tract hypoplasia and absence of the septum pellucidum and, in two-thirds of patients hypothalamic-pituitary dysfunction. IMAGING FINDINGS : CT In addition to enlarged lateral ventricles with an absent septum pellucidum, CT may demonstrate small optic apparatus (best seen with volumetric scanning and coronal reformats) and associated small bony optic foramina. MRI MRI is the modality of choice for assessing septo-optic dysplasia. may show a "point down" appearance of the lateral ventricular frontal horns on coronal images absent septum pellucidum hypoplastic pituitary stalk hypoplastic optic chiasm/optic nerves and globes
Findings
Evidence of absence of septum pellucidum with fusion of frontal horns and body of bilateral lateral ventricles in midline. Evidence of cerebrospinal fluid filled linear cleft extending from ependymal surface of body of right lateral ventricle opening into pial surface of parietal region, lined by thickened grey matter with irregular margin of lateral ventricle. Thinning of bilateral optic nerves and optic chiasma noted. Right Perisylvian polypachygyriform complex noted. Interhemispheric fissure noted. Features suggstive of septo optic dysplasia with right parietal open lip schizencephaly and right perisylvian polypachygyria.
Discussion
Septo-optic dysplasia , also known as de Morsier syndrome, is a condition characterised by optic nerve/tract hypoplasia and absence of the septum pellucidum and, in two-thirds of patients hypothalamic-pituitary dysfunction. IMAGING FINDINGS : CT In addition to enlarged lateral ventricles with an absent septum pellucidum, CT may demonstrate small optic apparatus (best seen with volumetric scanning and coronal reformats) and associated small bony optic foramina. MRI MRI is the modality of choice for assessing septo-optic dysplasia. may show a "point down" appearance of the lateral ventricular frontal horns on coronal images absent septum pellucidum hypoplastic pituitary stalk hypoplastic optic chiasm/optic nerves and globes
Note:
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!
We do not discourage differential diagnosis. But all the differentials must satisfy the findings noted in the case.
If you feel you have answered rightly but cannot find your name in the above list, please call 09551942599.
Did you Know?
The order in which the names appear in this winner's list is based on the time of submission. The first person to send the correct answer gets his/her name on top of the list!